Letybo® (letibotulinumtoxinA-wlbg), sometimes referred to as “K-tox,” is an FDA-approved neuromodulator used to temporarily improve moderate to severe glabellar lines, the vertical “11” lines between the eyebrows. Approved in February 2024, Letybo is part of the same family of botulinum toxin type A injectables as Botox, Dysport, Xeomin, Jeuveau, and Daxxify.
At Orenda Med Spa, we use neuromodulators like Letybo to create natural-looking wrinkle reduction while preserving facial expression.
How Letybo Works
Letybo is a purified botulinum toxin type A that works by temporarily relaxing targeted facial muscles.
It blocks the release of acetylcholine, the chemical messenger that tells muscles to contract. When the muscle relaxes, the overlying skin smooths—reducing the appearance of dynamic wrinkles caused by repetitive facial movements like frowning or squinting.
Results typically last 3–4 months, after which the muscle activity gradually returns and maintenance treatment is recommended.
Letybo vs. Other Neuromodulators
Similarities
- FDA-approved for glabellar lines
- Works by relaxing facial muscles
- Results last approximately 3–4 months
- Possible mild side effects such as redness, swelling, bruising, headache, or temporary eyelid drooping
Differences
- Some patients report a quicker onset, with visible effects in as little as 1–3 days (full results at 14 days).
- Developed using advanced purification processes and formulated without complexing proteins.
- Backed by Phase III clinical trials.
- Often competitively priced compared to other neurotoxins.
Important: Neuromodulator units are not interchangeable between brands. Proper dosing and expert injection techniques are essential for safe, balanced results.
What to Expect During Your Letybo Treatment at Orenda
Your appointment begins with a comprehensive facial consultation, including review of your medical history, muscle strength, and aesthetic goals. Treatment is fully customized.
- Initial visit: 30–60 minutes
- Treatment time: just a few minutes
- Minimal discomfort (topical numbing available)
- Small temporary bumps at injection sites may appear and resolve within 10–15 minutes
- Little to no downtime
- Avoid rubbing the area and hold exercise for 24 hours
- Most patients return to normal activities immediately.
Expected Results
Letybo provides:
- Noticeable softening of frown lines
- A smoother, refreshed appearance
- Natural-looking results without appearing “frozen”
Results vary based on metabolism, muscle strength, lifestyle, and treatment area.
Who Should Avoid Letybo?
Letybo may not be appropriate if you:
- Are allergic to botulinum toxin type A
- Have an infection at the injection site
- Have certain neuromuscular disorders
- Are pregnant or breastfeeding
- Have difficulty swallowing or breathing disorders
A thorough consultation ensures safe candidacy.
Potential Side Effects
Common (usually mild and temporary):
- Headache
- Redness or swelling
- Bruising
- Temporary eyelid or brow drooping (rare)
Rare but serious:
- Difficulty swallowing or breathing
- Vision changes
- Excessive muscle weakness
- Seek immediate medical care if serious symptoms occur.
Why Choose Letybo at Orenda?
Letybo is a science-backed, FDA-approved neuromodulator offering effective, natural wrinkle reduction. While newer to the U.S. market, it follows the same trusted mechanism as established neurotoxins, with emerging data supporting its safety and performance.
At Orenda, treatment is never one-size-fits-all. Proper assessment, advanced injection technique, and customized dosing ensure beautiful, balanced outcomes.
Contact us to set up an appointment or call (720) 519-0223
